| 产品名 | 产品编码 | 产品包装 （DMSO溶液/10mM） |
| 黄酮类活性化合物库 Target Probe+ | LA-1003 | 96孔板： 10 μL/well, 20 μL/well, 或100 μL/well |
黄酮类化合物广泛存在于自然界的植物中，属植物次生代谢产物。黄酮类化合物是以黄酮(2-苯基色原酮)为母核而衍生的一类黄色色素。黄酮类化合物广泛存在于植物体内，具有强抗氧化性、抑菌抑酶特性、抗肿瘤等多功效的天然产物。
黄酮类活性化合物库 Target Probe+
图 1 黄酮类活性化合物已知相关疾病领域
表2 黄酮类活性化合物药物靶点示例
| Cytochrome P450 1A2/1B1/1A1 (by homology) | Xanthine dehydrogenase/oxidase | Aldehyde oxidase (by homology) | Microtubule-associated protein tau |
| Aldose reductase | Aldo-keto reductase family 1 member B15/B10 (by homology) | NADPH oxidase 4 | Alcohol dehydrogenase [NADP(+)] (by homology) |
| 1,5-anhydro-D-fructose reductase (by homology) | Multidrug resistance-associated protein 1 | Canalicular multispecific organic anion transporter 1/2 (by homology) | Sodium/glucose cotransporter 1/2 |
| Low affinity sodium-glucose cotransporter | ATP-binding cassette sub-family G member 2 | Carbonyl reductase [NADPH] 1/3 | Plasmin light chain B |
| Apolipoprotein(a) (by homology) | Estradiol 17-beta-dehydrogenase 1 | Retinol dehydrogenase 8 (by homology) | Tyrosyl-DNA phosphodiesterase 1 |
| [flavin-containing] A/B (by homology) | Beta amyloid A4 protein | Adenosine receptor A3/A1 | Cyclin-dependent kinase 1/2/3/4/6 |
| Muscleblind-like protein 1/2 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A (by homology) | Alpha-2A adrenergic receptor | Prostaglandin G/H synthase 1/2 (by homology) |
| Nitric oxide synthase | Aldehyde dehydrogenase | Cytosolic 10-formyltetrahydrofolate dehydrogenase (by homology) | Mitochondrial 10-formyltetrahydrofolate dehydrogenase (by homology) |
| 3-oxo-5-alpha-steroid 4-dehydrogenase 1 | cGMP-specific 3',5'-cyclic phosphodiesterase | Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (by homology) | Epidermal growth factor receptor |
| Receptor tyrosine-protein kinase erbB-2 (by homology) | ERBB4 intracellular domain (by homology) | Carbonic anhydrase | Beta-secretase 1/2 |
| 3-phosphoinositide-dependent protein kinase 1 | Cyclic AMP-responsive element-binding protein 1 | FAD-linked sulfhydryl oxidase ALR | Arachidonate 12-lipoxygenase, 12S-type (by homology) |
| Induced myeloid leukemia cell differentiation protein Mcl-1 | 22 kDa interstitial collagenase | Stromelysin-1/-2 | Macrophage metalloelastase |
